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Supplements That Will Increase Testosterone

Supplements That Will Increase Testosterone

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The Human Effect Matrix summarizes human studies to tell you what effects Boron has on your body, how much evidence there is, and how strong these effects are.

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Level of Evidence

? The amount of high quality evidence. The more evidence, the more we can trust the results.

Outcome Magnitude of effect

? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.

Consistency of research results

? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.

Notes
grade-c

C-Reactive Protein (CRP)

Notable Very High See all 5 studies

Most studies found notable reductions, with calcium fructoborate being the most supported form.

grade-d

Cramps

Notable - See study

One study in young women found a meaningful improvement in pain and duration of menstrual cramps.

grade-d

Erythrocyte Sedimentation Rate

Notable Very High See 2 studies

There was a notable reduction with low, medium, or high doses in people with osteoarthritis. and rheumatoid arthritis.

grade-d

Interleukin 1-beta

Notable - See study

There was a notable reduction in one study in healthy participants, with no notable difference between 1.5 mg and 3 mg of calcium fructoborate.

grade-d

Interleukin 6

Notable Very High See 2 studies

Notable reductions have been found in people with rheumatoid arthritis and healthy participants.

grade-d

N-terminal Prohormone of Brain Natriuretic Peptide

Notable - See study

There was a notable reduction in one study, when taken on its own or combined with resveratrol compared with control and resveratrol alone.

grade-d

PMS

Notable - See study

One study in young women found a modest improvement in pain and duration of menstrual cramps. No other symptoms of PMS have been evaluated.

grade-d

Pain

Notable - See study

There was a notable reduction in knee pain in one study on people with knee discomfort.

grade-d

Symptoms of Osteoarthritis

Notable - See study

There was a notable reduction in overall symptoms in a study on people with knee discomfort but who hasn't necessarily been diagnosed with osteoarthritis of the knee.

grade-d

Symptoms of Rheumatoid Arthritis

Notable - See study

There was a notable reduction from sodium tetraborate and calcium fructoborate in one small study. Calcium fructoborate looked somewhat more potent.

grade-d

TNF-Alpha

Notable - See study

There was a notable reduction in one study on people with rheumatoid arthritis. Calcium fructoborate was more effective than sodium tetraborate.

grade-d

Estrogen


Minor
Low See all 3 studies

Appears to influence estrogen, seems unreliable in its mechanisms and is likely context dependent. Both increases and decreases have been noted

grade-d

Fibrinogen

Minor - See study

There was somewhat of a reduction in people with osteoarthritis in one study.

grade-d

Free Testosterone

Minor Very High See 2 studies

Appears to be somewhat effective, but requires some more robust trials

grade-d

Homocysteine

Minor - See study

There was a small decrease in healthy participants in one study.

grade-d

Inflammation

Minor - See study

Some influence on typically inflammatory cytokines, practical relevance of these changes unknown

grade-d

Interleukin 1-alpha

Minor - See study

Calcium fructoborate led to a notable reduction in one study in participants with rheumatoid arthritis, while calcium tetraborate only led to a small reduction.

grade-d

Kidney Stones

Minor - See study

Appears effective, but no comparison to a reference drug nor control group thus far

grade-d

Liver Enzymes


Minor
- See study

One crossover study found a small increase in alkaline phosphatase when boron was taken second, but not when taken first. More research is needed to verify this.

grade-d

Low-density lipoprotein (LDL)

Minor High See all 3 studies

Somewhat of a reduction in participants with high LDL has been noted in 3 studies.

grade-d

Lymphocyte Count

Minor - See study

A small reduction was noted in one study. More studies are needed to verify this.

grade-d

Monocyte Chemoattractant Protein-1

Minor - See study

There was a reduction in one study on healthy participants. 3 mg of boron from calcium fructoborate was modestly more effective than 1.5 mg.

grade-d

Serum Magnesium

Minor - See study

There was somewhat of an increase in one study from 3 mg of chelates of citrate, aspartate, and glycinate.

grade-d

Serum T3


Minor
- See study

There was both an increase and a decrease in a crossover trial when boron was taken first or second.

grade-d

Serum T4


Minor
- See study

There was both a small increase and a decrease in a crossover study depending on whether boron was taken first or second.

grade-d

Testosterone

Minor High See all 3 studies

There appears to be somewhat of an interaction with boron and testosterone in both genders, but it is seemingly unreliable

grade-d

Thyroid-Stimulating Hormone


Minor
- See study

While not statistically significant, boron saw a small increase when taken first in a crossover trial, but not when taken second.

grade-d

Total cholesterol

Minor Very High See all 3 studies

Studies have generally found a small reduction in people with elevated levels.

grade-d

White Blood Cell Count

Minor - See study

There was somewhat of an increase in one study of peri-menopausal women. More research is needed to verify this.

grade-d

Blood glucose

- - See study

There was no effect in participants with healthy blood sugar levels in one study.

grade-d

Body Fat

- - See study

No apparent effect in one study of normal weight males.

grade-d

Cortisol

- - See study

No significant effect on cortisol has been noted with supplemental boron

grade-d

DHT

- - See study

No significant influences on serum DHT noted

grade-d

Follicle-Stimulating Hormone

- - See study

There was an increase in one crossover study when it was taken second, but not when it was taken first.

grade-d

High-density lipoprotein (HDL)

- High See all 3 studies

Studies don't suggest a meaningful effect overall.

grade-d

Lean Mass

- - See study

No apparent effect in one study.

grade-d

Plasma Calcium

- - See study

No apparent effect in one study from 3 mg of chelates of citrate, aspartate, and glycinate.

grade-d

Strength

- - See study

No apparent effect on 1-rep max squats and benchpress in men involved in a training program.

grade-d

Triglycerides

- High See all 3 studies

The studies don't consistently suggest a meaningful effect

Supplements That Will Increase Testosterone

Source: https://examine.com/supplements/boron/

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